Hemoglobin S
نویسندگان
چکیده
منابع مشابه
Nitrite Versus S-Nitroso-Hemoglobin
Arecent flurry of research papers and commentaries in this journal1–4 has highlighted a current major controversy in cardiovascular biochemistry and physiology: how is nitric oxide (NO) transported in the bloodstream. Two views have arisen. First, that S-nitrosated hemoglobin and albumin serve as stable storage forms of intravascular NO, and, in the case of S-nitrosated hemoglobin, as an allost...
متن کاملInfluence of Hemoglobin S Adducts on Hemoglobin A 2 Quantification
ical goal for imprecision (CV) was 13.6% [3]. Thus the performances of all of the methods may be satisfactory. However, as Fraser and Peterson have argued, even when biological variation, not analytical variation, is the limiting source of variation in a test, there is still great advantage in using a method with the least possible imprecision and bias [4]. The aca V was the least precise instr...
متن کاملAcceleration of hemoglobin C crystallization by hemoglobin S.
We previously reported that circulating hemoglobin (Hb) CC erythrocytes contain oxygenated HbC crystals with little or no HbF and that HbF inhibits in vitro crystallization of HbC. We now report that HbS accelerates in vitro crystallization of HbC. Crystals were formed in 1.8 mol/L potassium phosphate buffer, pH 7.4, at 30 degrees C and were counted in several time intervals with a hematocytome...
متن کاملLow proportions of glycosylated hemoglobin associated with hemoglobin S and hemoglobin C.
Using a cation-exchange chromatographic method, we found normal or subnormal values for glycosylated hemoglobin in a few diabetic patients with persistent hyperglycemia. Subsequent investigations revealed that these unexpected results had originated from black patients with diabetes. In view of common occurrence of abnormal hemoglobins in the Negro population, we subjected blood preparations to...
متن کاملAggregation of hemoglobin S and hemoglobin CHarlem with nonsickle hemoglobin in concentrated phosphate buffer.
The effect of HbA and HbF on both the aggregation and deaggregation of deoxy HbS and deoxy HbCHarlem in concentrated phosphate buffers was studied by a turbidimetric method. Although pure deoxy HbA is fully soluble in 2.4 M potassium phosphate buffer, the same concentration of deoxy HbAS was insoluble in the same buffer. Since there was little dissolved hemoglobin in the solute of a mixture of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2015
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2014.232868